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Myocardial reperfusion is the main issue for percutaneous coronary intervention (PCI). We sought to evaluate the usefulness of coronary sinus filling time (CSFT) to assess outcome after PCI for left anterior descending coronary artery (LAD).
We assessed the CSFT after performing successful PCI for patients with single LAD significant stenosis. Patients were classified into two groups (unfavorable and favorable) based on the Clinical and echocardiographic follow-up along 6 months following PCI. Coronary sinus was visualized in appropriate views after PCI and CSFT in seconds was derived from frame count. Thrombolysis in Myocardial Infarction (TIMI) flow grade and corrected TIMI (cTIMI) frame count were assessed.
There was 36 patients in unfavorable group and 52 in favotable outcome group. Among the unfavorable group 69.4% were females against 44.2% in the favorable group group. Comparing favorable group with unfavorable group, the were 32 patients (91.6%) had typical angina versus 11 patients (21%), E/E' was 18+2.1 versus 7+1.9 (P<0.0001), EF% was 32.3+6.1% versus 59.5+5.7% (P<0.001), and instent stenosis was 7 (19.4%) vesus 2 (3.8%); P<0.003. Mean CSFT was 6.21 ± 0.45 s in unfavorable group versus 3.32 ± 0.74 s in the favorable group (P<0.001). No significant differences were found after PCI between both groups with respect to cTIMI frame count (p >0.05). CSRT of >5.0s was the best cut-of value predicting unfavorable coutcome after PCI for LAD.
CSFT is a simple method to predict outcome of PCI. CSFT was significantly delayed in patients with unfavorable outcome. CSFT may be used as a simple and quantitative test in percutaneous coronary intervention to select patients and predict outcome after PCI.