Author + information
The aim of this study is to investigate whether age increase affects the decision to use drug-eluting stents (DES) in elderly patients undergoing percutaneous coronary intervention (PCI).
This is a single center registry including elderly patients (≥ 65 year-old) undergoing PCI. We defined first DES era as the period between April 2003 and July 2008, and second DES era the period of July 2008 to March 2014. Multivariable model was created for both eras to assess the independent factors associated with DES implantation and the impact of age (per 10 year increase).
A total of 8,598 elderly patients were included, of whom 4,528 (52.7%) and 4,070 (47.3%) underwent PCI in the first and second generation DES eras, respectively. Multivariable logistic regression showed that age increase of per 10 years was associated with less likelihood to receive DES implantation. Similarly, patients with acute myocardial infarction, chronic renal insufficiency, chronic heart failure, cardiac shock and current smoking were less likely to receive DES in the two DES eras.
Among elderly patients undergoing PCI, age is independently associated with a lower likelihood of DES implantation in the second generation era. This finding may highlight the clinical difficulty in assessing the risk/benefit balance of DES in the elderly population.