Table 2

Procedural Characteristics

Clopidogrel +
Prasugrel
(n = 427)
Prasugrel
(n = 447)
p Value
No. of lesions treated602566
Lesions treated1.41 ± 0.731.28 ± 0.600.003
Treated vessels
 Left main coronary artery7 (1.6)2 (0.5)0.10
 Left anterior descending artery185 (43.4)209 (47.2)0.28
 Left circumflex artery85 (20.0)73 (16.5)0.19
 Right coronary artery200 (46.9)184 (41.5)0.12
 Bypass graft2 (0.5)2 (0.5)1.00
Intravenous vasopressors10 (2.3)13 (2.9)0.68
Baseline TIMI flow in infarct vessel0.05
 0 or 1329 (54.9)332 (61.5)
 299 (16.5)68 (12.6)
 3171 (28.5)140 (25.9)
Primary PCI procedure
 No. of stents per lesion1.32 ± 0.641.26 ± 0.530.34
 Type of stent
  Drug-eluting stent401 (70.2)359 (69.0)0.79
  Bare metal stent172 (30.1)162 (31.2)0.76
 Total stent length per lesion, mm25.1 ± 13.7025.8 ± 12.70.75
 Average stent diameter, mm3.1 ± 0.53.2 ± 0.70.06
 Direct stenting154 (27.0)189 (36.4)0.65
 Maximal balloon pressure, atm14.5 ± 3.714.5 ± 3.60.87
 Overlapping stents implanted135 (23.6)110 (21.2)0.33
 Successful thrombus aspiration131 (30.7)163 (36.5)0.71
Final TIMI flow in infarct vessel0.78
 0 or 14 (0.7)6 (1.1)
 220 (3.3)18 (3.2)
 3577 (96.0)531 (95.7)

Values are mean ± SD or n (%).

Patients grouped according to the loading dose, already on a daily maintenance dose, or immediate post-procedure exposure.

PCI = percutaneous coronary intervention; TIMI = Thrombolysis In Myocardial Infarction.

  • p values pairwise (prasugrel + clopidogrel vs. prasugrel alone) from chi-square, Fisher exact test, or t test; p values from mixed models accounting for lesions nested within patients for lesion-level data.

  • Visible thrombus obtained.