Table 3

Enrollment Summary and Baseline Data

Bolus InjectionProlonged Infusion
ControlAdenosineControlAdenosine
Enrollment summary
 Animals entered11112622
  Exclusions
   Technical failure0311
   Staining failure1001
  Death
   Nonconvertible ventricular fibrillation during occlusion0324
   Acute pump failure0021
   Final number entered in analysis1052115
Baseline data
 Animal weight, kg56 ± 158 ± 253 ± 151 ± 1
 Male/female3/73/212/97/8
  Myocardial masses, g
   Left ventricle118 ± 5130 ± 4125 ± 3119 ± 3
   Area-at-risk30 ± 138 ± 433 ± 128 ± 2

Values are n or mean ± SEM.

  • Technical difficulties resulting in failure to complete the experimental protocol.

  • Staining difficulties compromising accurate measurement of infarct size and/or no-reflow.

  • Occurring during the first 40 min of occlusion, that is, prior to adenosine treatment; none of the animals developed nonconvertible ventricular fibrillation during reperfusion.