Table 1

Baseline Characteristics

All
(n = 583)
Transfemoral
(n = 499)
Nontransfemoral
(n = 84)
Age, yrs83 (78–87)84 (79–88)81 (74–84)
Female237 (40.7)188 (37.7)49 (59.0)
STS PROM, %6 (4–8)6 (4–8)7 (4–10)
Valve area, cm20.7 (0.6–0.8)0.7 (0.6–0.8)0.7 (0.6–0.8)
Mean gradient, mm Hg41 (31–52)41 (31–52)38 (31–52)
Pacemaker73 (16.3)60 (16.0)13 (17.8)
Prior angioplasty156 (26.8)132 (26.5)24 (28.6)
Prior coronary bypass138 (23.7)114 (22.8)24 (28.6)
Prior AVR43 (7.4)34 (6.8)9 (10.7)
Bridging valvuloplasty43 (7.4)32 (6.4)11 (13.1)
Severe COPD72 (12.3)61 (12.2)11 (13.1)
Dialysis21 (3.6)18 (3.6)3 (3.6)
Severe CKD62 (10.7)51 (10.3)11 (13.1)
Porcelain aorta47 (8.1)28 (5.6)19 (22.6)
NYHA functional class III/IV480 (82.3)404 (81.0)76 (90.5)
LVEF ≤30%26 (4.5)24 (4.9)2 (2.4)

Values are median (interquartile range) or n (%).

AVR = aortic valve replacement; CKD = chronic kidney disease; COPD = chronic obstruction pulmonary disease; LVEF = left ventricular ejection fraction; NYHA = New York Heart Association; STS PROM = Society of Thoracic Surgeons predicted risk of mortality.