Table 1

Baseline Characteristics According to Symptom Onset-to-Balloon Time

SBT ≤2 h
(n = 162)
SBT >2 to 4 h
(n = 976)
SBT >4 h
(n = 918)
Combined
(n = 2,056)
p Value
All Groups
Age, yrs54.1 (49.1–62.4)58.3 (50.7–68.3)61.4 (53.4–80.0)59.2 (51.8–69.2)<0.0001
Men85.2 (138/162)77.0 (752/976)74.8 (687/918)76.7 (1,577/2,056)0.02
Body mass index, kg/m227.13 (24.79–30.86)27.13 (24.61–30.10)27.00 (24.45–30.25)27.06 (24.54–30.25)0.75
Hypertension51.2 (83/162)49.1 (479/976)53.5 (491/918)51.2 (1,053/2,056)0.16
Hyperlipidemia46.9 (76/162)43.3 (423/976)41.5 (381/918)42.8 (880/2,056)0.39
Smoking66.7 (108/162)65.9 (641/973)64.0 (584/912)65.1 (1,333/2,047)0.64
Diabetes mellitus9.9 (16/162)14.4 (141/976)18.5 (170/918)15.9 (327/2,056)0.005
Prior myocardial infarction9.3 (15/162)10.2 (100/976)10.5 (96/918)10.3 (211/2,056)0.90
Prior PCI11.7 (19/162)12.0 (117/976)8.4 (77/917)10.4 (213/2,055)0.03
Prior coronary artery bypass graft surgery0.6 (1/162)2.4 (23/976)2.8 (26/918)2.4 (50/2,056)0.24
Prior angina11.7 (19/162)17.8 (174/976)27.5 (252/917)21.7 (445/2,055)<0.0001
History of congestive heart failure1.9 (3/162)2.2 (21/976)2.8 (26/918)2.4 (50/2,056)0.56
Killip class 195.1 (154/162)91.1 (888/975)90.3 (828/917)91.0 (1,870/2,054)0.15
Peripheral vascular disease0.6 (1/162)3.8 (37/975)4.7 (43/918)3.9 (81/2,055)0.05
History of renal insufficiency1.2 (2/162)3.2 (31/975)3.2 (29/918)3.0 (62/2,055)0.38
PCI to left anterior descending artery41.0 (71/173)42.4 (446/1,052)41.2 (412/1,000)41.8 (929/2,225)0.84
Pre-PCI TIMI 3 flow13.9 (24/173)18.6 (196/1,051)20.2 (202/999)19.0 (422/2,223)0.13
Post-PCI TIMI 3 flow97.1 (168/173)95.1 (1,000/1,052)88.9 (889/1,000)92.4 (2,057/2,225)<0.0001
Clopidogrel administration100.0 (162/162)99.9 (975/976)99.6 (914/918)99.8 (2,051/2,056)0.27
Glycoprotein IIb/IIIa inhibitor use59.9 (97/162)53.6 (523/976)55.7 (510/915)55.0 (1,130/2,053)0.28
Drug-eluting stent70.4 (112/159)73.2 (687/939)70.5 (606/859)71.8 (1,405/1,957)0.43
Bare-metal stent30.8 (49/159)28.0 (263/939)30.7 (264/859)29.4 (576/1,957)0.41
Door-to-balloon time, min58 (47–73)93 (71–115)120 (87–172)98.00 (72–133)<0.0001
Procedural success90.8 (178/196)90.3 (1,072/1,187)82.7 (918/1,110)87.0 (2,168/2,493)<0.0001
Left ventricular ejection fraction, %50.00 (45.00–55.00)50.00 (45.00–59.00)50.00 (40.00–58.00)50.00 (43.00–58.00)0.23

Values are median (interquartile range) or % (n/N).

PCI = percutaneous coronary intervention; SBT = symptom onset-to-balloon time; TIMI = Thrombolysis In Myocardial Infarction.

  • TIMI flow grade 3 plus residual stenosis <50%.