Table 1

Clinical and Pre- and Post-Procedural Angiographic Characteristics

Scaffold Oversize Group
(n = 649)
Scaffold Nonoversize Group
(n = 583)
p Value
Age, yrs61.6 ± 10.760.8 ± 10.10.20
Male73.8 (479)75.1 (438)0.60
Current smoker1.7 (141)24 (140)0.34
Hypertension requiring treatment67.6 (439)67.9 (396)0.95
Dyslipidemia requiring treatment69.8 (453)69 (402)0.76
Any diabetes mellitus24 (156)26.2 (153)0.39
Unstable angina24.8 (161)22.9 (133)0.46
Prior history of myocardial infarction28.1 (182)27.8 (162)0.95
Lesion location
 Right coronary artery21.9 (142)33.6 (196)<0.01
 Left anterior descending artery49.8 (323)41.9 (244)0.01
 Left circumflex artery or ramus9.9 (64)9.6 (56)0.92
 Left main coronary artery0 (0)0.2 (1)0.47
ACC/AHA lesion complexity
 A1.9 (12)2.1 (12)0.84
 B153.9 (349)52.8 (307)0.73
 B241.2 (267)43.5 (25)0.45
 C3.1 (20)1.7 (10)0.14
TIMI flow grade 0 or 10.6 (4)0.2 (1)0.38
Calcification (moderate or severe)13.4 (87)14.4 (84)0.62
Angulation ≥45°2.6 (17)2.2 (13)0.71
Bifurcation4.0 (26)4.8 (28)0.58
Thrombus1.5 (10)1.9 (11)0.67
Pre-procedural
 Reference vessel diameter, mm2.50 ± 0.332.79 ± 0.39<0.01
 Proximal Dmax, mm2.66 ± 0.303.11 ± 0.34<0.01
 Distal Dmax, mm2.58 ± 0.312.94 ± 0.38<0.01
 Minimal lumen diameter, mm1.05 ± 0.301.15 ± 0.33<0.01
 Diameter stenosis, %57.9 ± 10.958.6 ± 10.20.22
 Obstruction lesion length, mm12.2 ± 5.913.0 ± 5.70.03
Device related
 2.5-mm scaffold8.6 (56)13.9 (81)<0.01
 3.0-mm scaffold82.4 (535)77.4 (451)0.03
 3.5-mm scaffold8.9 (58)8.8 (51)0.92
 Average nominal diameter2.97 ± 0.243.00 ± 0.210.03
Post-procedural
 Reference vessel diameter, mm2.58 ± 0.302.82 ± 0.34<0.01
 Minimal lumen diameter, mm2.19 ± 0.282.37 ± 0.31<0.01
 Diameter stenosis, %15.3 ± 6.515.9 ± 10.20.09
 Acute decrease, % diameter stenosis42.5 ± 12.542.5 ± 12.40.98
 Acute gain, mm1.13 ± 0.341.21 ± 0.38<0.01
 Acute gain/pre-procedural RVD, mm0.46 ± 0.140.44 ± 0.140.02
 Bailout treatment with metallic stent1.9 (12)0.7 (4)0.08

Values are mean ± SD, or % (n).

Clinical and pre- and post-procedural angiographic characteristics are according to the distribution of Dmax measurements minus the nominal scaffold size in the scaffold oversize group versus the scaffold nonoversize group.

ACC/AHA = American College of Cardiology/American Heart Association lesion characteristics; Dmax = maximal lumen diameter; RVD = reference vessel diameter; TIMI = Thrombolysis In Myocardial Infarction.