Table 1

Baseline Clinical and Echocardiographic Characteristics

OverallBPD GroupNo-BPD Groupp Value
Clinical variables
 Age, yrs81.6 ± 6.580.5 ± 7.981.9 ± 6.10.007
 Female52.5 (723/1,376)38.2 (104/272)56.1 (619/1,104)<0.001
 Hypertension81.3 (1,117/1374)80.8 (219/271)81.4 (898/1103)0.820
 Diabetes mellitus29.1 (398/1,370)26.8 (72/269)29.6 (326/1,101)0.357
 Atrial fibrillation5.4 (74/1374)5.9 (16/271)5.3 (58/1103)0.673
 Previous myocardial infarction17.6 (241/1,370)18.1 (49/270)17.5 (192/1100)0.789
 Previous stroke/TIA11.3 (155/1376)14.3 (39/272)10.5 (116/1,104)0.073
 Previous CABG14.8 (203/1,374)18.1 (49/271)14.0 (154/1,103)0.087
 Previous PCI30.1 (412/1,368)26.6 (72/271)31.0 (340/1,097)0.007
 PVD29.3 (403/1,374)33.2 (90/271)28.4 (313/1,103)0.117
 COPD23.7 (325/1,374)24.7 (67/271)23.4 (258/1,103)0.644
 CRF25.9 (308/1,191)23.9 (58/243)26.4 (250/948)0.427
 Previous PPM13.1 (174/1,326)14.0 (37/264)12.9 (137/1,062)0.631
 NYHA functional class III or IV73.4 (1010/1,376)80.9 (220/272)71.6 (790/1,104)0.002
 Previous SAVR2.4 (33/1,374)4.1 (11/271)2.0 (22/1,103)0.047
 STS score, %7.1 (4–13)7.5 (4–14)6.9 (5–13)0.711
Echocardiographic variables
 LVEF, %50.7 ± 12.648.0 ± 13.751.4 ± 12.20.001
 Mean aortic gradient, mm Hg51.7 ± 15.551.8 ± 15.751.7 ± 15.40.430
 AVA, cm20.4 ± 0.20.4 ± 0.20.4 ± 0.20.610
 Moderate or severe MR44.9 (583/1,297)53.8 (135/251)42.8 (448/1,046)0.002

Values are mean ± SD or n/N (%).

AVA = aortic valve area; BPD = balloon post-dilation; CABG = coronary artery bypass graft; COPD = chronic obstructive pulmonary disease; CRF = chronic renal failure; LVET = left ventricular ejection fraction; MR = mitral regurgitation; NYHA = New York Heart Association; PCI = percutaneous coronary intervention; PPM = permanent pacemaker; PVD = peripheral vascular disease; SAVR = surgical aortic valve replacement; STS = Society of Thoracic Surgery; TIA = transient ischemic attack.

  • Defined as a glomerular filtration rate <30 ml/min.