Table 6

Log-Rank Test in High-Risk Subsets of Patients

High OTRCYP2C19 Variants
Diabetes mellitus0.010.02
CKD0.030.02
Age >75 yrs0.810.03
Multivessel disease0.530.04
LVEF <40%0.960.04

Abbreviations as in Tables 1 and 3.

  • On-treatment platelet reactivity, assessed by the VerifyNow P2Y12 test (P2Y12 reaction units ≥230).

  • Composite of CYP2C19 variants: CYP2C19*2 (681 G>A), CYP2C19*3 (636 G>A), CYP2C19*4 (1 A>G), CYP2C19*5 (1,297 C>T), and CYP2C19*17 (806 C>T).