Table 4

Baseline Clinical and Echocardiographic Characteristics for RESPOND Extension Cohort (N = 50)

Patient characteristics
 Age, yrs80.9 ± 8.2
 Female54
 STS score4.4 ± 3.1
 Katz Index Activities of Daily Living Score5.9 ± 0.4
 Diabetes mellitus, medically treated30
 COPD, moderate or severe2
 NYHA functional class III or IV52
 Atrial fibrillation, history34
 Coronary artery disease, history62
 Prior PCI28
 Prior CABG14
 Cerebrovascular accident, history12
 Prior implanted pacemaker10
 Echocardiographic assessments, core lab
  Aortic valve area (effective orifice area), cm20.7 ± 0.2
  Mean aortic valve gradient, mm Hg39.8 ± 13.7
  Peak aortic valve gradient, mm Hg64.0 ± 19.5
  Left ventricular ejection fraction, %50.2 ± 9.3
  Aortic regurgitation, moderate or severe17.8
Procedural characteristics
 Valve system implanted
  23 mm17 (34)
  25 mm33 (66)
 Vascular access
  Transfemoral48 (96)
  Transaortic2 (4)
  Subclavian0 (0)

Values are mean ± SD, %, or n (%).

Abbreviations as in Table 1.

  • Risk scores were not routinely collected/reported by all study centers.

  • Severe in 1 patient (2.2%).