Table 4

Clinical Outcomes at 30 Days in Radial Versus Femoral Access According to Sex

Male PatientsFemale Patientsp For Interaction
Radial (n = 3,126)Femoral (n = 3,046)Rate Ratio (95% CI)p ValueRadial (n = 1,071)Femoral (n = 1,161)Rate Ratio (95%CI)p Value
Death, MI, stroke272 (8.7)288 (9.5)0.92 (0.77–1.09)0.3197 (9.1)141 (12.2)0.73 (0.56–0.95)0.0190.15
Death, MI, stroke, BARC type 3 or 5299 (9.6)325 (10.8)0.89 (0.76–1.05)0.16111 (10.4)161 (13.9)0.73 (0.56–0.93)0.0120.18
Death, MI, stroke, BARC type 3 or 5, TVR, ST307 (9.9)329 (10.9)0.90 (0.77–1.06)0.21112 (10.5)162 (14.0)0.73 (0.57–0.93)0.0120.15
Death40 (1.3)51 (1.7)0.76 (0.50–1.15)0.2026 (2.4)40 (3.5)0.70 (0.43–1.15)0.150.79
Death cardiovascular39 (1.2)49 (1.6)0.77 (0.51–1.18)0.2325 (2.3)36 (3.1)0.75 (0.45–1.25)0.260.92
MI228 (7.4)232 (7.7)0.95 (0.79–1.15)0.6271 (6.7)98 (8.5)0.77 (0.56–1.05)0.100.25
Stroke12 (0.4)8 (0.3)1.46 (0.60–3.57)0.414 (0.4)8 (0.7)0.54 (0.16–1.78)0.300.18
TIA2 (0.1)4 (0.1)0.49 (0.09–2.65)0.393 (0.3)9 (0.8)0.36 (0.10–1.32)0.110.78
TVR39 (1.3)26 (0.9)1.46 (0.89–2.40)0.1310 (0.9)14 (1.2)0.77 (0.34–1.73)0.520.18
ST definite26 (0.8)19 (0.6)1.33 (0.74–2.41)0.344 (0.4)8 (0.7)0.54 (0.16–1.78)0.300.18
 Acute18 (0.6)8 (0.3)2.19 (0.95–5.06)0.0583 (0.3)4 (0.3)0.81 (0.18–3.61)0.780.24
 Subacute9 (0.3)11 (0.4)0.79 (0.33–1.92)0.611 (0.1)4 (0.4)0.27 (0.03–2.40)0.210.35
ST definite/probable35 (1.1)28 (1.0)1.22 (0.74–2.00)0.447 (0.7)10 (0.9)0.75 (0.29–1.98)0.560.38
 Acute20 (0.6)10 (0.3)1.95 (0.91–4.17)0.0804 (0.4)4 (0.3)1.08 (0.27–4.31)0.920.46
 Subacute17 (0.5)18 (0.6)0.92 (0.47–1.78)0.803 (0.3)6 (0.5)0.54 (0.13–2.15)0.370.49
Bleeding236 (7.6)418 (13.9)0.53 (0.45–0.62)<0.0001114 (10.7)188 (16.5)0.63 (0.50–0.80)0.00010.23
 BARC type 1113 (3.6)214 (7.1)0.50 (0.40–0.63)<0.000155 (5.2)92 (8.2)0.63 (0.45–0.89)0.00730.27
 BARC type 285 (2.7)153 (5.1)0.53 (0.41–0.70)<0.000142 (4.0)62 (5.4)0.72 (0.49–1.08)0.110.21
 BARC type 337 (1.2)56 (1.9)0.64 (0.42–0.97)0.03417 (1.6)28 (2.5)0.65 (0.35–1.19)0.160.97
 BARC type 3a18 (0.6)29 (1.0)0.60 (0.33–1.08)0.08711 (1.0)15 (1.3)0.79 (0.36–1.72)0.550.59
 BARC type 3b17 (0.5)25 (0.8)0.66 (0.36–1.22)0.186 (0.6)12 (1.1)0.54 (0.20–1.43)0.210.72
 BARC type 3c2 (0.1)3 (0.1)0.65 (0.11–3.88)0.630 (0.0)1 (0.1)0.36 (0.01–8.83)1.000.46
 BARC type 45 (0.2)5 (0.2)0.97 (0.28–3.36)0.961 (0.1)1 (0.1)1.08 (0.07–17.16)0.960.95
 BARC type 56 (0.2)0 (0.0)12.67 (0.71–224.81)0.0314 (0.4)11 (1.0)0.39 (0.12–1.23)0.0950.0033
 BARC type 5a3 (0.1)0 (0.0)6.82 (0.35–131.98)0.253 (0.3)9 (0.8)0.36 (0.10–1.32)0.110.022
 BARC type 5b3 (0.1)0 (0.0)6.82 (0.35–131.98)0.251 (0.1)2 (0.2)0.54 (0.05–5.95)0.610.094
 BARC type 3 or 543 (1.4)56 (1.9)0.74 (0.50–1.11)0.1421 (2.0)39 (3.4)0.58 (0.34–0.98)0.0400.45
 BARC type 3 or 5 access site8 (0.3)25 (0.9)0.31 (0.14–0.69)0.00238 (0.8)18 (1.6)0.48 (0.21–1.10)0.0750.47
 BARC type 3 or 5 non–access site35 (1.2)31 (1.0)1.10 (0.68–1.78)0.7113 (1.2)21 (1.8)0.66 (0.33–1.33)0.240.24
 BARC type 2, 3, or 5127 (4.1)208 (6.9)0.58 (0.47–0.73)<0.000162 (5.8)99 (8.6)0.66 (0.48–0.92)0.0120.51
 BARC type 2, 3, or 5 access site36 (1.2)129 (4.3)0.27 (0.18–0.39)<0.000133 (3.1)68 (5.9)0.51 (0.34–0.78)0.00160.021
 BARC type 2, 3, or 5 non–access site92 (3.0)84 (2.8)1.06 (0.79–1.43)0.6829 (2.7)31 (2.7)1.01 (0.61–1.67)0.980.85
 TIMI major19 (0.6)19 (0.6)0.97 (0.51–1.84)0.937 (0.7)18 (1.6)0.42 (0.17–1.00)0.0430.12
 TIMI minor15 (0.5)17 (0.6)0.86 (0.43–1.72)0.669 (0.8)15 (1.3)0.64 (0.28–1.48)0.290.61
 TIMI major/minor34 (1.1)36 (1.2)0.92 (0.57–1.47)0.7216 (1.5)33 (2.9)0.52 (0.28–0.94)0.0290.14
 GUSTO severe17 (0.5)15 (0.5)1.10 (0.55–2.21)0.796 (0.6)12 (1.0)0.54 (0.20–1.43)0.210.24
 GUSTO moderate14 (0.5)17 (0.6)0.80 (0.39–1.62)0.539 (0.9)15 (1.3)0.64 (0.28–1.47)0.290.69
 GUSTO mild206 (6.6)385 (12.8)0.50 (0.42–0.60)<0.0001100 (9.4)164 (14.5)0.64 (0.49–0.82)0.00050.13
 GUSTO moderate/severe31 (1.0)32 (1.1)0.94 (0.57–1.54)0.8115 (1.4)27 (2.4)0.59 (0.32–1.12)0.100.26
Composite of surgical access site repair and blood transfusion26 (0.9)35 (1.2)0.72 (0.43–1.20)0.2015 (1.4)38 (3.3)0.42 (0.23–0.77)0.00350.18
Surgical access site repair2 (0.1)9 (0.3)0.22 (0.05–1.00)0.0312 (0.2)6 (0.5)0.36 (0.07–1.78)0.190.65
Blood transfusion25 (0.9)30 (1.0)0.81 (0.48–1.38)0.4315 (1.4)34 (3.0)0.47 (0.26–0.87)0.0130.19

Values are n (%), unless otherwise indicated.

Abbreviations as in Tables 1, 2, and 3.