Table 4

Unadjusted and Adjusted Risk for 3-Year Clinical Outcomes Across Quartiles of Total Stent Length per Lesion

n (KM %)Log-Rank p ValueAdjustedp Value for Trend
HR (95% CI)p Value
MACE<0.00010.002
 Quartile 199 (12.0%)Reference
 Quartile 2165 (11.7%)0.95 (0.72–1.25)0.708
 Quartile 3136 (13.9%)0.99 (0.75–1.31)0.953
 Quartile 4229 (18.2%)1.38 (1.07–1.78)0.014
Key safety endpoint<0.00010.004
 Quartile 168 (8.2%)Reference
 Quartile 299 (7.1%)0.98 (0.70–1.37)0.896
 Quartile 384 (8.5%)0.96 (0.69–1.35)0.953
 Quartile 4158 (12.3%)1.48 (1.09–2.01)0.013
All-cause death<0.00010.558
 Quartile 139 (5.1%)Reference
 Quartile 258 (4.3%)0.97 (0.63–1.50)0.896
 Quartile 384 (8.5%)1.08 (0.70–1.68)0.718
 Quartile 468 (6.1%)1.09 (0.72–1.67)0.677
Cardiac death<0.00010.376
 Quartile 121 (2.7%)Reference
 Quartile 225 (3.1%)0.94 (0.51–1.74)0.852
 Quartile 335 (4.0%)1.44 (0.81–2.56)0.209
 Quartile 434 (4.4%)1.17 (0.66–2.08)0.598
Myocardial infarction<0.0001<0.0001
 Quartile 130 (3.4%)Reference
 Quartile 249 (3.4%)1.16 (0.71–1.90)0.553
 Quartile 341 (3.8%)1.08 (0.66–1.77)0.770
 Quartile 499 (7.1%)2.05 (1.32–3.20)0.001
Definite or probable ST<0.00010.944
 Quartile 110 (1.1%)Reference
 Quartile 218 (1.2%)0.79 (0.33–1.89)0.602
 Quartile 34 (0.4%)0.27 (0.08–0.88)0.030
 Quartile 420 (1.5%)1.00 (0.44–2.28)0.998
TLR<0.00010.366
 Quartile 144 (5.2%)Reference
 Quartile 286 (6.1%)0.86 (0.57–1.27)0.442
 Quartile 358 (6.2%)0.83 (0.55–1.27)0.396
 Quartile 496 (8.1%)1.10 (0.74–1.62)0.641

The key safety endpoint was defined as a composite of all-cause death, myocardial infarction, or definite or probable ST. MACE was defined as a composite of all-cause death, myocardial infarction, or TLR.

Abbreviations as in Table 3.

  • Adjusted for the following variables using a frailty model: age, hypertension, diabetes, smoking, prior PCI, prior myocardial infarction, PCI indication, and American College of Cardiology/American Heart Association lesion type B2/C.

  • Adjusted for the above variables with trial included as an additional covariate.