Table 2

5-Year Event Rates in the Randomized PLATINUM Trial

PtCr-EES (n = 758)CoCr-EES (n = 749)Hazard Ratio (95% CI)p Value
Target lesion failure9.1 (66)9.3 (66)0.97 (0.69–1.37)0.87
 Cardiac death2.6 (19)3.5 (25)0.74 (0.41–1.35)0.32
  Related to target vessel2.6 (19)2.7 (19)0.97 (0.52–1.84)0.94
  Not related to target vessel0.0 (0)0.8 (6)0.01
 Myocardial infarction3.4 (24)3.2 (23)1.02 (0.58–1.81)0.94
  Related to target vessel1.9 (14)2.3 (17)0.80 (0.40–1.63)0.55
  Not related to target vessel1.5 (10)1.2 (8)1.22 (0.48–3.10)0.67
Ischemia-driven TLR5.3 (38)6.2 (44)0.84 (0.54–1.29)0.43
All-cause death7.2 (52)7.8 (56)0.90 (0.62–1.32)0.60
All-cause death or MI10.3 (74)10.3 (74)0.98 (0.71–1.35)0.88
Ischemia-driven TVR9.9 (71)10.0 (70)0.98 (0.71–1.37)0.92
Ischemia-driven non-TL TVR5.8 (41)4.8 (33)1.21 (0.77–1.92)0.41
Target vessel failure13.1 (95)12.4 (88)1.05 (0.79–1.40)0.74
Stent thrombosis
 Definite0.8 (6)0.7 (5)1.18 (0.36–3.85)0.79
  Acute (<24 h)11
  Subacute (1–30 days)02
  Late (30 days to 1 yr)20
  Very late (>1 yr)32
 Probable0.0 (0)0.0 (0)
 Possible0.0 (0)0.0 (0)

Values are Kaplan-Meier estimated event rates expressed as % (n events) unless otherwise indicated.

CI = confidence interval; MI = myocardial infarction; PLATINUM = PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions; TL = target lesion; TLR = target lesion revascularization; TVR = target vessel revascularization.