Table 1

Characteristics of Included Studies

Study (Ref. #)YearCountryType of StudyTotal Population, nEnrollment Start DateEnrollment End DateSingle/MulticenterFollow-Up Duration, yrsBalloon-/Self-Expanding Valve, %TF/Non-TF Access, %
Ontario Cardiac Registry (13)2017CanadaProspective observational99920072013Multicenter3.5054/4671/29
Levi et al. (15)2017IsraelProspective observational56020082016Single5.0027/7386/14
Brazilian TAVI Registry (14)2017BrazilProspective observational81920082015Multicenter1.3627/7394/6
STS/ACC TVT Registry (16)2016United StatesProspective observational23,65220112014Multicenter1.0087/1360/40
US CoreValve Trial Registry (17)2016United StatesRetrospective from RCT3,687NRNRMulticenter1.000/10080/20
FRANCE 2 Registry (21)2016FranceProspective observational4,20120102012Multicenter3.0067/3374/26
PARTNER trial (18)2016United States/Canada/GermanyRetrospective from RCT2,55920072012Multicenter1.00100/058/42
PARTNER 2 Sapien 3 trial (19)2016United States/CanadaRetrospective from RCT1,66120132014Multicenter1.00100/0NR
Woitek et al. (20)2016GermanyProspective observational2,00420062015Single2.00NRNR
UK TAVI Registry (27)2015United KingdomProspective observational3,81320072012Multicenter2.0052/4871/29
Yakubov et al. (28)2015United StatesProspective observational489NRNRNR2.00100/0100/0
German TAVI Registry (29)2014GermanyProspective observational20120092010Multicenter1.009/9190/10
Italian CoreValve Registry (7)2013ItalyProspective observational65920072009Multicenter1.100/10090/10
D’Ascenzo et al. (6)2013ItalyProspective observational37720072011Multicenter1.3547/5385/15
Hayashida et al. (9)2012FranceProspective observational26020062010Single1.0085/1565/35
Humphries et al. (8)2012CanadaProspective observational58420052011Multicenter2.0097/3NR
Tamburino et al. (30)2011ItalyProspective observational663NRNRNR1.000/10090/10

NR = not reported; RCT = randomized clinical trial; STS/ACC = Society of Thoracic Surgeons/American College of Cardiology; TF = transfemoral.

  • Access was mainly transfemoral.