Table 4

Outcome Rates at 6 Years and Unadjusted and Adjusted HRs for Clinical Outcomes, According to AF Status

OutcomesTotal (n = 10,027)Non-AF (n = 9,316)AF (n = 711)Unadjusted HRp ValueAdjusted HRp Value
Primary outcome
 Composite of CV death, MI, or stroke748 (9.1)616 (8.0)132 (22.1)2.85 (2.40–3.39)<0.0012.33 (1.95–2.79)<0.001
Secondary outcomes
 Death265 (3.3)216 (2.9)49 (8.1)2.96 (2.23–3.91)<0.0011.72 (1.29–2.31)<0.001
  Cardiovascular109 (1.3)84 (1.1)2 (4.2)3.97 (2.64–5.98)<0.0012.09 (1.35–3.22)<0.001
  Noncardiovascular156 (2.0)132 (1.9)24 (4.1)2.35 (1.59–3.47)<0.0011.45 (0.97–2.17)0.07
 MI433 (5.3)380 (5.0)53 (9.0)1.90 (1.46–2.48)<0.0011.83 (1.40–2.39)<0.001
 Stroke253 (3.2)185 (2.5)68 (12.0)4.64 (3.60–5.99)<0.0013.33 (2.54–4.35)<0.001
  Ischemic182 (2.4)125 (1.7)57 (10.1)5.54 (4.16–7.39)<0.0014.00 (2.96–5.42)<0.001
  Hemorrhagic47 (0.6)39 (0.6)8 (1.5)3.07 (1.59–5.92)<0.0012.36 (1.19–4.65)0.01
 Definite stent thrombosis45 (0.6)38 (0.6)7 (1.2)2.42 (1.19–4.95)0.012.86 (1.37–5.96)0.005
 Repeat revascularization1,089 (13.5)994 (13.2)95 (16.9)1.24 (1.02–1.51)0.031.35 (1.11–1.64)0.003
 Bleeding328 (4.2)274 (3.7)54 (9.9)2.53 (1.94–3.30)<0.0011.93 (1.47–2.54)<0.001
  Major133 (1.8)111 (1.5)22 (4.5)2.68 (1.78–4.03)<0.0012.01 (1.32–3.06)0.001
  Nonmajor195 (2.5)163 (2.2)32 (5.4)2.43 (1.71–3.45)<0.0011.88 (1.31–2.69)<0.001

Event rates are shown as Kaplan-Meier estimates, n (%). HRs are for the AF group as compared with the non-AF group.

CI = confidence interval; CV = cardiovascular; other abbreviations as in Table 1.

  • Models were adjusted for age, sex, the presence or absence of prior HF, the presence or absence of prior stroke history, the presence or absence of peripheral vascular disease, the presence or absence of chronic renal failure, and clinical indication for PCI (stable angina, unstable angina, NSTEMI, or STEMI).