Table 3

Clinical Outcomes to 4 Yrs in Patients Treated for Proximal LAD Vs. Nonproximal LAD

30 Days6 Months1 Yr2 Yrs3 Yrs4 Yrs
Proximal LAD (n = 2,525)Nonproximal LAD (n = 6,156)p ValueProximal LAD (n = 2,520)Nonproximal LAD (n = 6,133)p ValueProximal LAD (n = 2,518)Nonproximal LAD (n = 6,112)p ValueProximal LAD (n = 2,507)Nonproximal LAD (n = 6,084)p ValueProximal LAD (n = 2,491)Nonproximal LAD (n = 6,041)p ValueProximal LAD (n = 2,459)Nonproximal LAD (n = 5,973)p Value
MACE3.4 (86)2.9 (181)0.2735.4 (137)4.6 (282)0.1107.5 (188)6.2 (376)0.02710.5 (264)8.6 (526)0.00712.7 (317)11.3 (684)0.07015.0 (369)13.7 (821)0.139
Death0.7 (17)0.3 (19)0.0251.1 (28)0.8 (48)0.1621.7 (42)1.3 (79)0.1903.2 (79)2.8 (169)0.3574.4 (109)4.3 (261)0.9075.8 (143)5.8 (348)>0.999
Cardiac death0.6 (16)0.3 (18)0.0351.0 (24)0.6 (37)0.0891.3 (33)0.9 (56)0.1022.2 (56)1.6 (95)0.0373.1 (76)2.3 (141)0.0593.6 (89)3.0 (178)0.132
MI3.0 (77)2.5 (152)0.1403.6 (90)2.7 (166)0.0363.9 (99)2.8 (174)0.0104.8 (120)3.3 (201)0.0015.4 (134)4.1 (249)0.0136.2 (152)4.9 (290)0.015
TV MI3.0 (77)2.4 (148)0.0883.5 (89)2.6 (160)0.0233.8 (95)2.7 (166)0.0104.3 (107)3.0 (184)0.0054.7 (117)3.6 (219)0.0235.3 (130)4.2 (248)0.024
Emergent CABG0.1 (2)0.2 (10)0.5280.1 (3)0.2 (11)0.7690.3 (8)0.2 (13)0.3470.4 (9)0.2 (14)0.3570.4 (11)0.3 (17)0.2970.5 (12)0.4 (21)0.344
TLF3.4 (85)2.8 (171)0.1435.3 (133)4.3 (261)0.0417.0 (177)5.6 (341)0.0119.3 (234)7.1 (435)<0.00111.0 (274)8.9 (535)0.00312.3 (302)10.4 (620)0.013
TVF3.5 (89)3.0 (187)0.2526.1 (154)5.1 (313)0.0678.7 (219)7.0 (430)0.00911.2 (281)9.3 (568)0.00913.3 (331)11.5 (696)0.02314.8 (363)13.5 (805)0.127
Clinically driven TLR0.5 (12)0.5 (28)0.8632.0 (50)1.6 (96)0.1693.5 (88)2.6 (157)0.0224.8 (121)3.4 (207)0.0025.5 (138)4.2 (253)0.0076.1 (150)4.9 (291)0.024
Clinically driven TVR0.6 (16)0.8 (50)0.4182.8 (71)2.6 (159)0.5575.3 (133)4.3 (261)0.0477.1 (178)5.9 (361)0.0458.4 (209)7.3 (440)0.0809.4 (230)8.6 (513)0.272
Stent thrombosis0.8 (21)0.6 (36)0.1911.0 (25)0.7 (42)0.1391.2 (29)0.8 (50)0.1381.6 (40)1.1 (64)0.0391.8 (44)1.5 (91)0.3912.1 (52)2.0% (121)0.800
Hemorrhagic stroke while on clopidogrel0.0 (1)0.1 (5)0.6790.1 (2)0.1 (8)0.7340.1 (3)0.2 (13)0.4250.1 (3)0.3 (17)0.2200.2 (4)0.3 (20)0.2600.2 (5)0.4 (22)0.290

Values are % (n).

MACE included all-cause death, MI (Q-wave and non–Q-wave), emergent CABG surgery, or repeat clinically indicated target lesion percutaneous or surgical revascularization.

CABG = coronary artery bypass graft; MACE = major adverse cardiac events; TV MI = MI not clearly attributable to a nontarget vessel; TLF = target lesion failure; TLR = target lesion revascularization; TVF = target vessel failure; other abbreviations as in Table 1.