Table 1

Baseline Clinical, Angiographic, and Procedural Characteristics of Patients With ISR

First Procedure
(n = 79)
Index Procedure
(n = 75)
Clinical
 Age, yrs64 ± 1165 ± 11
 Male66 (83)63 (84)
 Currently smoking15 (19)10 (13)
 Hypercholesterolemia35 (44)33 (44)
 Hypertension37 (47)34 (45)
 Diabetes40 (51)37 (49)
 Clinical presentation
  Stable angina11 (14)17 (23)
  Unstable angina49 (62)49 (65)
  Acute myocardial infarction15 (19)4 (5)
  Silent myocardial ischemia4 (5)5 (7)
Angiographic
 LV ejection fraction, %54 ± 1451 ± 12
 Medina classification
  1,1,142 (53)10 (13)
  1,1,019 (24)4 (5)
  1,0,111 (14)11 (15)
  0,1,13 (4)4 (5)
  1,0,0013 (18)
  0,1,03 (4)10 (13)
  0,0,11 (1)23 (31)
 Main vessel reference, mm3.7 ± 0.3
 Side branch reference, mm2.8 ± 0.3
 Minimal lumen diameter, mm0.71 ± 0.30.71 ± 0.4
Procedural
 Main vessel stent diameter3.5 ± 0.23.4 ± 0.4
 Maximal pressure, atm16 ± 218 ± 3
 Bifurcation treatment
  Simple69 (87)44 (58)
  Complex10 (13)31 (42)
 Type of stent
  Sirolimus32 (41)18 (24)
  Paclitaxel26 (33)25 (33)
  Everolimus20 (25)20 (27)
  Zotarolimus1 (1)12 (16)
 Lesions treated at remote sites54 (68)28 (37)
 IVUS57 (72)59 (79)
 IABP4 (5)7 (9)

Values are mean ± SD or n (%).

IABP = intra-aortic balloon pump; ISR = in-stent restenosis; IVUS = intravascular ultrasound; LV = left ventricular.

  • Patients who presented with restenosis at follow-up.

  • Patients with restenosis treated percutaneously.

  • At the worst point of the 3 segments.