Table 1

Individual Characteristics of Included Studies

Study/First Author (Ref. #)
TEMPURA (15)RADIAL-AMI (16)FARMI (17)Li et al. (18)Yan et al. (19)RADIAMI (20)Gan et al. (21)Hou et al. (22)RADIAMI II (23)RIFLE-STEACS (11)RIVAL (12)STEMI-RADIAL (13)
Year200320052007200720082009200920092011201220122012
Mean age, yrs6755595670.859.552.9565.5559.6655962
Female, %17.91215.83425.23219.529.53626.720.933
No. of centers1Multiple111121141584
Patients, N149501143701031001952001081,0011,958707
Primary PCI, %, TRA/TFAAll36/3245.6/56.1NRAllAllAllAllAll91.8/9387.3/88.8NA
Gp IIb/IIIa Inhibitors, %, TRA/TFANone95/92NRNRAll44/4231.1/34.3All51/5467.4/69.934.5/31.145/45
MACE definitionDeath
MI
TLR
NoneNoneNoneDeath
MI
TVR
Death
MI
Death
MI
CABG
TLR
Death
MI
TVR
Death
MI
CABG
TVR
Death
MI
Stroke
TLR
Death
MI
Stroke
Death
MI
Stroke
Sheath size, ≤6-F/≥7-FNRTRA: 100%/0%
TFA: 88%/12%
100%/0%NRNR100%/0%NRNR100%/0%TRA: 81.4%/18.6%
TFA: 90.8%/9.2%
TRA:
98.6%/1.4%
TFA: 95.5%/4.5%
TRA: 100%/0%
TFA: 99.2%/0.8%
Crossover, %TRA to TFA, %TFA to TRA0%,
1.4%
4%,
0%
12.3%,
1.8%
1.6%,
1.1%
1.8%,
0%
8%,
2%
1.1%,
0%
4%,
0%
4.1%,
1.7%
9.4%,
2.8%
5.3%,
1.6%
3.7%,
0.6%
Bleeding definition usedStudy page 27 (15)Study page 544 (16)TIMINoneTIMIStudy page 334 (20)NoneStudy page 159 (22)Study page 765 (23)TIMITIMIHORIZONS-AMI
Follow-up durationHospital/9 monthsHospital/30 daysHospitalHospital30 daysHospitalHospital/6 months30 daysHospital30 days30 days30 days

FARMI = Five French Arterial Access With Reopro in Myocardial Infarction; Gp = glycoprotein; HORIZONS-AMI = Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction; MACE = major adverse cardiac events; MI = myocardial infarction; NA = not applicable; No. = Numbers; NR = not reported; PCI = percutaneous coronary intervention; RADIAL AMI = Radial versus femoral access for emergent percutaneous coronary intervention with adjunct glycoprotein IIb/IIIa inhibition in acute myocardial infarction; RADIAMI = Radial Versus Femoral Approach for Percutaneous Coronary Interventions in Patients With Acute Myocardial Infarction; RIFLE-STEACS = Radial Versus Femoral Randomized Investigation in ST-Elevation Acute Coronary Syndrome; RIVAL = RadIal Vs femorAL access for coronary intervention trial; STEMI-RADIAL = A Prospective Randomized Trial of Radial vs. Femoral Access in Patients With ST-Segment Elevation Myocardial Infarction; TEMPURA = Test for Myocardial Infarction by Prospective Unicenter Randomization for Access Sites; TFA = transfemoral approach; TIMI = Thrombolysis In Myocardial Infarction; TLR = target lesion revascularization; TRA = transradial approach; TVR = target vessel revascularization.

  • Exact number not reported in manuscript.

  • Nonprimary PCI were: rescue PCI (RADIAL-AMI, RIFLE-STEACS), rescue PCI + facilitated PCI (FARMI), and Secondary PCI (i. e., facilitated, rescue, or routine adjunctive) (RIVAL).

  • TIMI major vascular bleeding. 5-F or 6-F sheaths.