Table 1

Clinical Characteristics

HPR(n = 78)No HPR(n = 172)p Value
Age, yrs66.5 ± 9.665.4 ± 9.80.405
Male66 (85)134 (78)0.219
Body mass index, kg/m226.6 ± 3.125.9 ± 3.20.103
Diabetes mellitus33 (42)50 (29)0.039
Hypertension60 (77)128 (74)0.671
Hyperlipidemia60 (77)124 (72)0.422
Current smoker13 (17)40 (23)0.238
Previous myocardial infarction24 (31)44 (26)0.393
Previous coronary intervention28 (36)73 (42)0.329
Previous bypass surgery4 (5)9 (5)0.972
Left ventricle ejection fraction, %56 ± 756 ± 80.842
Creatinine, mg/dl1.10 ± 0.311.11 ± 0.290.810
Baseline medications
 Aspirin78 (100)172 (100)1.000
 Clopidogrel9 (12)19 (11)0.909
 Statin69 (88)146 (85)0.450
 Calcium channel blocker20 (26)40 (23)0.207
 Proton pump inhibitor22 (28)48 (28)0.961
Clinical presentation0.571
 Stable angina14 (18)26 (15)
 Unstable angina64 (82)146 (85)
PRU281 ± 34173 ± 44<0.001

Values are mean ± SD or n (%).

HPR = high platelet reactivity; PRU = P2Y12 reaction unit.