Table 2

Procedural Characteristics by Tertile of Observed Stroke or Death Rates

Low
(n = 2,259)
Average
(n = 11,082)
High
(n = 6,040)
p Value
Observed stroke or death rate0 (0)182 (1.6)269 (4.5)<0.001
Age, yrs70.9 ± 10.470.6 ± 10.270.8 ± 10.50.22
Male1,382 (61.2)6,947 (62.7)3,624 (60.0)0.002
Body mass index, kg/m229.6 ± 17.129.5 ± 17.229.1 ± 16.80.30
Caucasian2,072 (91.7)10,252 (92.5)5,478 (90.7)<0.001
Hypertension2,040 (90.4)10,056 (90.9)5,471 (90.7)0.74
Dyslipidemia1,913 (84.8)9,822 (88.8)5,128 (85.0)<0.001
Diabetes876 (38.8)4,178 (37.8)2,254 (37.4)0.48
GFR <60 ml/min877 (40.7)4,031 (37.3)2,174 (37.4)0.01
Ischemic heart disease1,222 (54.3)6,219 (56.3)3,091 (51.2)<0.001
MI within 6 weeks56 (2.5)291 (2.6)140 (2.3)0.46
Impending major surgery76 (3.4)387 (3.5)218 (3.6)0.85
History of heart failure444 (19.7)1,744 (15.8)1,098 (18.2)<0.001
Atrial fibrillation315 (14.0)1,354 (12.3)806 (13.4)0.03
Dementia88 (3.9)279 (2.5)255 (4.2)<0.001
Previous ischemic stroke359 (15.9)1,567 (14.1)1,123 (18.6)<0.001
Previous ipsilateral CAS75 (3.3)374 (3.4)214 (3.5)0.81
Previous ipsilateral CEA438 (19.4)1,690 (15.2)1,105 (18.3)<0.001
Symptomatic target lesion979 (43.4)4,418 (40.0)2,758 (45.8)<0.001
Pre-procedure imaging
 Carotid duplex1,431 (64.3)7,323 (66.6)3,803 (63.3)0.02
 Magnetic resonance imaging206 (9.5)1,207 (11.0)770 (12.9)<0.001
 Computed tomography666 (30.3)3,076 (28.1)1,891 (31.6)0.01
Type III aortic arch216 (10.3)987 (10.0)552 (10.0)0.001
Visible thrombus present100 (4.5)335 (3.1)232 (3.9)<0.001
Ulceration574 (25.8)2,739 (25.3)1,871 (31.4)<0.001
Lesion length, mm21.1 ± 11.619.8 ± 9.919.5 ± 11.4<0.001
Percent of stenosis83.6 ± 11.584.7 ± 10.983.6 ± 11.4<0.001
Embolic protection attempted2,124 (94.5)10,781 (97.4)5,788 (95.9)<0.001

Values are n (%) or mean ± SD.

CAS = carotid artery stenting; CEA = carotid endarterectomy; GFR = glomerular filtration rate; MI = myocardial infarction.

  • All p values are <0.05 except where denoted by asterisk.