Table 1

Baseline Characteristics

Characteristics, % (n) or Mean ± SDAll Patients (n = 209)Aspirin Resistant (n = 9)Aspirin Sensitive (n = 176)Clopidogrel Low-Responder (n = 51)Clopidogrel Responder (n = 147)
Age (yrs)61.3 ± 9.963.6 ± 10.961.1 ± 10.060.6 ± 9.561.8 ± 10.2
Male80.9% (169)88.9% (8)81.3% (143)82.4% (42)82.3% (121)
Body mass index (kg/m2)28.4 ± 5.029.1 ± 7.128.3 ± 4.730.3 ± 5.327.8 ± 4.7
Prior PCI22.5% (47)22.2% (2)22.2% (39)29.4% (15)19.7% (29)
Prior CABG4.8% (10)0.0% (0)5.1% (9)7.8% (4)2.7% (4)
Prior MI30.6% (64)33.3% (3)30.7% (54)39.2% (20)27.9% (41)
Diabetes mellitus14.8% (31)22.2% (2)14.2% (25)19.6% (10)14.3% (21)
Hypertension57.4% (120)66.7% (6)58.0% (102)64.7% (33)53.7% (79)
Hyperlipidemia78.9% (165)88.9% (8)79.5% (140)68.6% (35)82.3% (121)
Active smoker23.0% (48)44.4% (4)22.2% (39)21.6% (11)23.8% (35)
PAD5.3% (11)11.1% (1)6.3% (11)2.0% (1)6.8% (10)
ACS57.4% (120)44.4% (4)59.1% (104)60.8% (32)53.7% (79)
Baseline laboratory results
 Creatinine93.1 ± 20.591.0 ± 17.393.0 ± 20.798.2 ± 23.991.6 ± 19.7
 Hemoglobin144.4 ± 13.8141.5 ± 12.2144.4 ± 13.8146.0 ± 15.8143.9 ± 13.3
 Platelet237.6 ± 58.9248.9 ± 67.5236.4 ± 59.4222.9 ± 56.1242.8 ± 60.2
 CRP7.0 ± 14.67.0 ± 7.77.2 ± 16.114.7 ± 25.94.5 ± 6.7
Pre-procedural medications
 CCB16.7% (35)0.0% (0)15.9% (28)17.6% (9)17.0% (25)
 ACE inhibitors71.3% (149)66.7% (6)72.2% (127)72.5% (37)70.1% (103)
 Beta blockers90.9% (190)88.9% (8)93.2% (164)98.0% (50)87.8% (129)
 Statins87.6% (183)66.7% (6)89.2% (157)88.2% (45)87.8% (129)
Procedural characteristics
 Integrilin 18 h49.3% (103)66.7% (6)50.0% (88)52.9% (27)48.3% (71)
 Integrilin duration (h)8.9 ± 8.312.1 ± 8.49.0 ± 8.39.2 ± 8.38.7 ± 8.3
 # of vessels treated1.3 ± 0.51.2 ± 0.41.3 ± 0.51.3 ± 0.61.2 ± 0.5
 # of lesions treated1.7 ± 0.91.4 ± 0.71.7 ± 1.01.9 ± 1.21.6 ± 0.8
 DES used36.8% (77)33.3% (3)35.8% (63)39.2% (20)36.7% (54)
 AHA B2 or C lesion64.8% (114)44.4% (4)64.7% (114)61.0% (25)66.4% (83)

ACE = angiotensin-converting enzyme; ACS = acute coronary syndrome; AHA = American Heart Association; CABG = coronary artery bypass surgery; CCB = calcium-channel blocker; CRP = C-reactive protein; DES = drug-eluting stent; MI = myocardial infarction; PAD = peripheral arterial disease.

  • p < 0.05.