Table 1

Clinical, Echocardiographic, and Procedure Characteristics of Patients Undergoing TAVI, According to Occurrence of at Least Moderate AR, Immediately After TAVI

VariablesOverall (n = 74)Paravalvular AR <2/4 (n = 58)Paravalvular AR ≥2/4 (n = 16)p Value
Clinical characteristics
 Age, yrs82 ± 881 ± 886 ± 50.03
 Sex (men)38 (51%)25 (43%)13 (81%)0.005
 Weight, kg69 ± 568 ± 1474 ± 180.20
 Height, cm163 ± 8161 ± 9170 ± 60.007
 BSA, m21.7 ± 0.21.7 ± 0.21.8 ± 0.20.19
Echocardiographic characteristics
 TTE systolic aortic annulus, mm22.9 ± 1.622.5 ± 1.724 ± 10.001
 TEE systolic aortic annulus, mm23.3 ± 1.723 ± 1.924.7 ± 1.20.002
 Ejection fraction, %51 ± 1749 ± 1756 ± 180.13
 Aortic valve area, cm20.67 ± 0.20.65 ± 0.20.71 ± 0.20.25
 Aortic valve mean gradient, mm Hg50 ± 1551 ± 1547 ± 130.18
 Asymmetric AV calcifications16 (35%)14 (38%)2 (22%)0.36
 Eccentric AV opening10 (16%)8 (17%)2 (14%)0.36
Procedure
 Implantation access (femoral)46 (62%)34 (59%)12 (75%)0.23
 Prosthesis size (26 mm)50 (66%)37 (64%)13 (81%)0.19
 Cover index, %6.7 ± 47.6 ± 53.2 ± 30.002

Values are mean ± SD or n (%).

AR = aortic regurgitation; AV = aortic valve; BSA = body surface area; TAVI = transcatheter aortic valve implantation; TEE = transesophageal echocardiography; TTE = transthoracic echocardiography.

  • Cover index defined as 100 × ([prosthesis diameter – TEE annulus diameter]/prosthesis diameter).