Table 1

2 Clinical Randomized Trials of MTH

Trial/Author (Ref. #)nTemp GoalDurationTime to TemperatureSurvivalSurvival With Favorable Neurological Function
HACA trial (11)
 Normothermia13762/138 (45%)54/138 (39%)
 Hypothermia13633°C24 h8 h81/137 (59%)75/137 (55%)
Bernard et al. (12)
 Normothermia3411/34 (32%)9/34 (26%)
 Hypothermia4333°C12 h2 h21/43 (49%)21/43 (49%)

Values are n/N (%).

HACA = Hypothermia After Cardiac Arrest; MTH = mild therapeutic hypothermia (32°C to 34°C).

  • p < 0.05 versus normothermic cohort.