Table 2

Observed and Predicted Rates (95% CI) for In-Hospital Mortality in the Entire Cohorts and Stratified by Type of ACS and Performing PCI

Risk Score by Groups of PatientsnCalibrationDiscriminationC-Statistic (95% CI)
Observed, %Expected, %H-L
Chi-Squarep Value
Original GRACE
Overall4,4975.9 (5.2–6.6)6.0 (5.3–6.6)8.1230.4220.907 (0.889–0.924)
STEMI1,4439.8 (8.2–11.3)9.8 (8.2–11.3)9.3700.3120.904 (0.879–0.929)
NSTE-ACS3,0544.2 (3.4–4.9)4.2 (3.4–4.9)7.9680.4370.899 (0.874–0.925)
PCI
 Yes2,7484.5 (3.7–5.2)4.5 (3.7–5.2)10.2430.2480.915 (0.889–0.942)
 No1,7498.3 (7.0–9.6)7.1 (5.9–8.3)9.6760.2890.897 (0.873–0.920)
Updated GRACE
Overall4,4975.9 (5.2–6.6)6.0 (5.3–6.6)7.3280.5020.896 (0.877–0.915)
STEMI1,4439.8 (8.2–11.3)9.8 (8.2–11.3)5.0600.7510.906 (0.881–0.931)
NSTE-ACS3,0544.2 (3.4–4.9)4.2 (3.4–4.9)6.5670.5840.883 (0.855–0.910)
PCI
 Yes2,7484.5 (3.7–5.2)4.5 (3.7–5.2)2.7910.9470.914 (0.887–0.941)
 No1,7498.3 (7.0–9.6)7.2 (6.0–8.4)8.9030.3510.880 (0.854–0.906)
AR-G
Overall4,4975.9 (5.2–6.6)5.8 (5.1–6.5)7.5870.4750.901 (0.883–0.919)
STEMI1,4439.8 (8.2–11.3)9.4 (7.9–10.9)2.9670.9360.894 (0.866–0.921)
NSTE-ACS3,0544.2 (3.4–4.9)4.1 (3.4–4.8)3.3220.8540.901 (0.876–0.927)
PCI
 Yes2,7484.5 (3.7–5.2)4.3 (3.6–5.1)7.1710.5180.916 (0.890–0.941)
 No1,7498.3 (7.0–9.6)7.5 (6.3–8.7)8.2230.4120.885 (0.860–0.911)

AR-G = ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry and the GTWG (Get With the Guidelines) Database; CI = confidence interval; GRACE = Global Registry of Acute Cardiac Events; NSTE-ACS = non–ST-segment elevation acute coronary syndrome; other abbreviations as in Table 1.