Table 1

Clinical and Angiographic Characteristics at Baseline

VariableYukon Choice (n = 120)Taxus Liberté (n = 116)p Value
Age, yrs67.0 ± 9.567.3 ± 9.10.81
Male83 (69)79 (68)0.97
Cardiovascular risk factors
 Current smoking28 (23)31 (27)0.65
 Hypertension118 (98)112 (97)0.65
 Peripheral artery disease17 (14)11 (10)0.36
 Family history of coronary artery disease46 (38)50 (43)0.54
Body mass index, kg/m231.0 ± 4.830.5 ± 4.70.39
Left ventricular ejection fraction, %57.6 ± 12.657.3 ± 11.00.87
HDL cholesterol, mmol/l1.24 ± 0.361.25 ± 0.330.80
LDL cholesterol, mmol/l2.89 ± 0.993.09 ± 1.060.16
Glycosylated hemoglobin, %7.2 ± 1.57.1 ± 1.20.75
Glomerular filtration rate, ml/min/1.73 m273.8 ± 23.474.7 ± 22.20.79
Prior myocardial infarction26 (22)26 (22)1.0
Prior percutaneous coronary intervention38 (32)33 (28)0.69
Prior coronary artery bypass grafting6 (5)12 (10)0.19
Medication
 Aspirin86 (72)85 (73)0.90
 Statin85 (71)79 (68)0.75
 ACE inhibitor or ARB105 (88)102 (88)1.0
 Beta blocker96 (80)87 (75)0.45
Diabetes mellitus
 Diet only24 (20)17 (15)0.36
 Diet + oral antidiabetics42 (35)50 (43)0.25
 Insulin54 (45)49 (42)0.77
Glycoprotein IIb/IIIa-inhibitor use8 (7)8 (7)1.0
Lesion length, mm13.7 ± 4.513.6 ± 6.40.87
Minimal luminal diameter, mm0.6 ± 0.30.6 ± 0.30.73
Reference diameter, mm2.90 ± 0.582.98 ± 0.580.34
Stenosis, % luminal diameter79 ± 980 ± 90.45
Lesion complexity according to AHA and ACC (10)0.20
 A23 (19)28 (24)
 B158 (48)41 (35)
 B221 (18)29 (25)
 C18 (15)18 (16)
Calcification18 (15)27 (23)0.16

Data are mean ± SD or n (%).

ACC = American College of Cardiology; ACE = angiotensin-converting enzyme; AHA = American Heart Association; ARB = angiotensin receptor blocker; HDL = high-density lipoprotein; LDL = low-density lipoprotein.

  • Estimated according to MDRD (Modification of Diet in Renal Disease) formula (15).