Author + information
- S1936879815021494-700cf5cb00fe36da60d3e624b1bc5958Ji Young Park1,
- S1936879815021494-83e45353357d710a9dde9c5071cfa225Seung-Woon Rha2,
- S1936879815021494-38f9379288aee4a50a9131fa84c4a249Byoung Geol Choi3,
- S1936879815021494-5ad2c1999ed23ad295759ce26e3acbe8Se Yeon Choi1,
- S1936879815021494-e7fb692d66d88666def902b2ab5ef87fJi Yeon Hong4 and
- S1936879815021494-53b75c6df57ff3836114113292e7ed5aSang Ho Park5
Peripheral arterial disease (PAD) is known to be associated with poor outcomes due to higher incidence of combined cardiovascular morbidity and mortality. We evaluated the clinical outcomes of hypertensive versus normotensive patients (pts) with PAD who underwent peripheral transluminal angioplasty (PTA).
The outcomes of 559 consecutive pts with symptomatic PAD who underwent PTA were enrolled for analysis. Pts were divided into two groups; PAD with hypertension (N=390) and PAD without hypertension (N=169). The incidence of restenosis, amputation rates and clinical outcomes were assessed at a follow-up of 1 year.
Hypertensive PAD pts had suffered from more diabetes mellitus (DM, 78.2% vs 64.5%; P=0.001), chronic kidney disease (CKD, 34.9% vs 13.0%; P<0.001), and need for dialysis (23.8% vs 8.9%; P<0.001). However, the incidence of wounds and claudication as the initial diagnosis for PAD were similar between the two groups. At 8 months follow-up, the incidence of binary restenosis, total occlusion of the limb were similar between the two groups. At 1-year follow up, the incidence of repeat PTA, amputation rate, and major adverse cardiovascular events (MACE) were similar between the two groups.
Although hypertensive PAD pts had higher comorbidity including DM and CKD, the incidence of restenosis and amputation rate, and MACE at 1 years following successful PTA were similar with those of PAD pts without hypertension.