Author + information
- Received March 23, 2016
- Accepted April 7, 2016
- Published online June 27, 2016.
- Chee Yang Chin, MD, MSca,b,c,
- Akiko Maehara, MDa,b,
- Khady Fall, MDb,
- Gary S. Mintz, MDa and
- Ziad A. Ali, MD, DPhila,b,∗ ()
- aCardiovascular Research Foundation, New York, New York
- bCenter for Interventional Vascular Therapy, Division of Cardiology, Presbyterian Hospital and Columbia University, New York, New York
- cDepartment of Cardiovascular Medicine, National Heart Centre Singapore, Singapore
- ↵∗Reprint requests and correspondence:
Dr. Ziad A. Ali, Columbia University, Medicine – Cardiovascular, 650 W. 168th Street, William Black Building, 8-801D, New York, New York 10032.
High-definition 60-MHz intravascular ultrasound (IVUS) represents the current state of the art in IVUS imaging, offering superior spatial resolution of <100 μm, faster catheter pull-back speeds up to 10 mm/s, and rapid image acquisition at 60 frames/sec, compared with conventional 40-MHz IVUS. High-definition IVUS maintains the potential benefits of IVUS over optical coherence tomography, namely, greater tissue penetration without the need for luminal blood clearance. Here, we compare selected coregistered slices of typical in vivo native and stented coronary vessel segments in real-world patients who were imaged by both high-definition IVUS using the Kodama catheter (ACIST Medical Systems, Eden Prairie, Minnesota) and optical coherence tomography using the Optis catheter (St. Jude Medical, St. Paul, Minnesota).
High-resolution imaging allows clear definition of healthy vessel layers (Figure 1A). In most cases, the superior tissue penetration of IVUS permits full vessel evaluation through fibrous (Figure 1B) and lipidic (Figure 1C) plaque, whereas optical coherence tomographic signals are strongly attenuated by lipid. Post-stenting appearances enable the assessment of tissue prolapse and subtle malapposition (Figure 1D) and the delineation of stent struts from underlying structures including calcium (Figure 1E). Side lobe artifacts from stent struts are more pronounced on IVUS (Figures 1D and 1E), and optical coherence tomography remains superior in the assessment of luminal structures, including intimal dissection (Figure 1F).
Dr. Chin has received honoraria from ACIST Medical Systems. Dr. Maehara has received grant support from Boston Scientific Corporation; and is a consultant for Boston Scientific Corporation and ACIST Medical Systems. Dr. Mintz has received grant support from Boston Scientific Corporation, Volcano Corporation, St. Jude Medical, and InfraRedX; and is a consultant for Boston Scientific Corporation and Volcano Corporation. Dr. Ali has received grant support from and is a consultant for St. Jude Medical and ACIST Medical Systems. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received March 23, 2016.
- Accepted April 7, 2016.
- American College of Cardiology Foundation