Author + information
- Aravind Sekhar1,
- Prafull Raheja1,
- Amr Mohsen1,
- Emily Anggelis2,
- Chris N. Anggelis2,
- Samantha L. Straton1,
- Brad Sutton1 and
- Michael P. Flaherty1
This was a prospective, single-center study evaluating the efficacy and cost effectiveness of early ambulation (within 30 min) following femoral artery closure with the
ProGlideR suture-mediated vascular closure device (PD) in patients undergoing diagnostic cardiac catheterization compared with manual compression.
It is unclear whether early ambulation with ProGlide is safe and translates into patient satisfaction and cost savings as compared with manual compression (MC).
Methods and Results
Inclusion criteria were met in 170 patients (85 PD and 85 MC patients). Following hemostasis, patients were ambulated 20 ft within 30 min (PD) or after the requisite 4 h recumbent time (MC) if feasible.
The primary endpoint was time-to-ambulation (TTA) following device closure. We also directly compared the safety of closure, times-to -hemostasis (TTH), -ambulation (TTA) and -discharge (TTD) with MC and, using a fully allocated cost model, performed cost analysis for both strategies. Multivariate analysis was used to determine predictors of patient satisfaction. The primary endpoint of safe, early ambulation was achieved following closure (mean of 27.1±14.9 min; 95% confidence interval [CI] 25.2-30.2). Predictors of patient satisfaction in the PD group were absence of pain during closure, decreased TTA, and drastic reductions in TTD; the latter contributed indirectly to significant cost-savings in the PD group (1,282.3 ±118.3 vs. 2,271.4 ±121.1 dollars, respectively; P<0.001) and incremental cost savings by strategy also favored closure over MC ($89,124.5).
ProGlide is safe and effective for femoral artery closure in patients who ambulate within 30 min after cardiac catheterization; all of which translated into improved patient satisfaction and substantial cost savings.