Author + information
- Wenjie Tian,
- Rebecca Torguson,
- Hideaki Ota,
- Thibault Lhermusier,
- Sarkis Kiramijyan,
- Marco De,
- Magalhaes Pereira,
- Nevin Baker and
- Ron Waksman
Little information was available regarding the clinical outcomes of drug-eluting stents (DES) in octogenarians with acute myocardial infarction (AMI). The aim of this study was to determine whether there are differences between non-ST- and ST-segment elevation myocardial infarction (STEMI) for octogenarians underwent DES implantation.
Clinical data of 164 octogenarians with STEMI (n=115) or non-STEMI (n=49) who received the treatment of DES were retrospectively analyzed. The primary endpoint was the rate of major adverse cardiac events (MACE).
The octogenarians with STEMI or non-STEME had similarly low ejection fraction (EF, 0.42±0.16 vs. 0.43±0.18, p=719) and comparatively high percentage of chronic renal insufficiency (23.4% vs. 25.7%, p=0.764). The patients with STEMI had higher in-hospital, but similar out-hospital occurrence of cardiac death compared to those with non-STEMI. There were no differences in rates of MACE (26.5% vs. 24.6%, p=0.790), all cause death (22.4% vs. 19.3%, p=0.646) and TLR (5.0% vs. 6.9%, p=1.000) between the two groups at 1 year follow-up.
The occurrence of MACE, mainly driven by all cause death, was high in octogenarians with AMI underwent DES. The octogenarians with STEMI had higher risk of in-hospital cardiac death, but comparable clinical outcomes compared to those with non-STEMI at 1 year follow-up.
|Clinical success (%)||95.7||83.7||0.022|
|in-hospital Cardiac death||2.6||14.3||0.008|
|1 year follow-up (%)|
|Cardiac death out-hospital||4.5||4.9||1.000|
MACE: Major adverse cardiac events; MI: Myocardial infarction; TLR: Target lesion revascularization