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QT dispersion (Qtd) is defined as the difference between the maximal and the minimal values of the QT through the peripheral and precordial leads. It is considered as an arrhythmogenic indice. Since acute ST-elevation myocardial infarction (STEMI) is associated with arrhythmias and cardiac arrest the aim of this study was to investigate the effect of revascularization on corrected QT interval (QTc) and Qtd.
We conducted a retrospective study in which patients presenting with acute STEMI who underwent primary percutaneous coronary intervention (PCI) were enrolled. Qtc and Qtd were calculated before, 90 minutes after, and 24 hours after the procedure.
Fifty-four patients (49 males, 5 females) with a mean age of 55,2 years were evaluated. The results showed significant reduction in both Qtc (mean 443 ms vs 439 ms ; p < 0,001) and Qtd (mean 59 vs 37 ; p < 0,001) before and 24 hours after primary PCI when no significant difference was noticed between the Qtc (443 vs 441 ; p = 0,17) and Qtd (59 vs 58 ; p = 0,15) before and 90 minutes after the procedure.
Our Study showed that primary PCI was effective in reducing Qtc and Qtd after 24 hours although it showed no effect on these arrhythmogenic indices 90 minutes after successful revascularization with PPCI. These findings suggest that ischemia-induced Qtd and prolonged Qtc are important arrhythmogenic parameters responding to successful PPCI and may be used as markers for successful PPCI after 24 hours.