JACC: Cardiovascular Interventions
Clinical Research
Anti-CD34 Antibodies Immobilized on the Surface of Sirolimus-Eluting Stents Enhance Stent Endothelialization
Gaku Nakazawa, Juan F. Granada, Carlos L. Alviar, Armando Tellez, Greg L. Kaluza, Margaret Yoklavich Guilhermier, Sherry Parker, Stephen M. Rowland, Frank D. Kolodgie, Martin B. Leon and Renu Virmani
Table 2
Table 2
Endothelialization by SEM From Phase 1: Overlapping and Nonoverlapping
| Overlapping Stent Zone | Nonoverlapping Stent Zone | ||||
|---|---|---|---|---|---|
| Stent Group (Proximal-Distal) | Location | Area Covered (%) | Stent Segment | Location | Area Covered (%) |
| GS–GS (n = 4) | Above struts | 95 ± 6 | GS segments (n = 8) | Above struts | 98 ± 3 |
| Between | 95 ± 5 | (in GS–GS) | Between | 99 ± 4 | |
| GS–SES (n = 4) | Above struts | 79 ± 5 | GS segment (n = 4) | Above struts | 100 ± 0 |
| (in GS–SES) | Between | 100 ± 0 | |||
| Between | 89 ± 3 | SES segment (n = 4) | Above struts | 62 ± 33 | |
| (in GS–SES) | Between | 88 ± 7 | |||
| SES–SES (n = 4) | Above struts | 36 ± 14 | SES segments (n = 8) | Above struts | 46 ± 20 |
| Between | 74 ± 10 | (in SES–SES) | Between | 85 ± 10 | |
| p value above struts | 0.007 | 0.0003 | |||
| p value between | 0.009 | 0.0006 | |||
Abbreviations as in Table 1.
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