Author + information
- Received August 18, 2008
- Revision received February 19, 2009
- Accepted March 8, 2009
- Published online May 1, 2009.
- ↵⁎Reprint requests and correspondence:
Dr. Fumiaki Ikeno, Stanford University, Division of Cardiovascular Medicine, 300 Pasteur Drive, Falk CVRB007, Stanford, California 94305
Scientific discoveries for improvement of human health must be translated into practical applications. Such discoveries typically begin at “the bench” with basic research, then progress to the clinical level. In particular, in the field of interventional cardiology, percutaneous cardiovascular intervention has rapidly evolved from an experimental procedure to a therapeutic clinical setting. Pre-clinical studies using animal models play a very important role in the evaluation of efficacy and safety of new medical devices before their use in human clinical studies. This review provides an overview of the emerging role, results of pre-clinical studies and development, and evaluation of animal models for percutaneous cardiovascular intervention technologies for patients with symptomatic cardiovascular disease.
- Received August 18, 2008.
- Revision received February 19, 2009.
- Accepted March 8, 2009.
- American College of Cardiology Foundation