In Vitro Relaxation Responses of Intramyocardial Resistance Arteries Distal to Stents
Cumulative concentration-relaxation curves for microvascular arteries distal to PES and BMS, and naïve vessels. (A) Relaxation to higher concentrations of endothelium-dependent vasodilator sP was inhibited in PES compared with relaxation in BMS (p < 0.05) and naïve (p < 0.001) vessels. (B) Relaxation to higher concentrations of endothelium-dependent (nonreceptor mediated) vasodilator A23187 was inhibited in coronary segments distal to PES compared with relaxation of naïve vessels (p < 0.05). (C) Relaxation to the highest concentration of the endothelium-independent dilator sodium nitroprusside was similar for PES, BMS, and naïve vessels (p = NS). Abbreviations as in Figure 1.