Author + information
- Received May 15, 2009
- Revision received June 16, 2009
- Accepted June 25, 2009
- Published online November 1, 2009.
- Hiram G. Bezerra, MD, PhD⁎,
- Marco A. Costa, MD, PhD⁎,⁎ (, )
- Giulio Guagliumi, MD‡,
- Andrew M. Rollins, PhD† and
- Daniel I. Simon, MD⁎
- ↵⁎Reprint requests and correspondence:
Dr. Marco A. Costa, Division of Cardiology, Heart & Vascular Institute, University Hospitals, Case Western Reserve University, 11100 Euclid Avenue, Lakeside 3001, Cleveland, Ohio 44106-5038
Cardiovascular optical coherence tomography (OCT) is a catheter-based invasive imaging system. Using light rather than ultrasound, OCT produces high-resolution in vivo images of coronary arteries and deployed stents. This comprehensive review will assist practicing interventional cardiologists in understanding the technical aspects of OCT based upon the physics of light and will also highlight the emerging research and clinical applications of OCT. Semi-automated imaging analyses of OCT systems permit accurate measurements of luminal architecture and provide insights regarding stent apposition, overlap, neointimal thickening, and, in the case of bioabsorbable stents, information regarding the time course of stent dissolution. The advantages and limitations of this new imaging modality will be discussed with emphasis on key physical and technical aspects of intracoronary image acquisition, current applications, definitions, pitfalls, and future directions.
Dr. Bezerra received research grants and consulting honoraria from Lightlab. Dr. Costa received research grants and consulting honoraria from Lightlab and Cordis/Johnson & Johnson. Dr. Guagliumi received research grants from Medtronic Vascular, Lightlab, and Boston Scientific. Dr. Simon received research grants from Medtronic Vascular and Cordis/Johnson & Johnson.
- Received May 15, 2009.
- Revision received June 16, 2009.
- Accepted June 25, 2009.
- American College of Cardiology Foundation