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Sleep Apnea (SA) has been noted to be prevalent in patients with valvular heart disorders including aortic stenosis. We evaluated the prevalence and predictors of sleep apnea (both obstructive-OSA and central-CSA) in a national sample of patients admitted for aortic valve replacement-both surgical (SAVR), and transcatheter (TAVR).
From 2011-2013, all patients undergoing SAVR and TAVR were identified from the National Inpatient Sample (NIS) data (representing 20% of all discharges in the US). All SA patients were identified with appropriate ICD 9 codes-(CSA- 327.21, OSA- 327.23, and unspecified-780.57). Prevalence and predictors for SA were noted in this cohort, in a multivariable-adjusted model.
Among 153,994 patients with aortic stenosis treated with TAVR or SAVR , 12,387 (8.04%%) patients had SA. 99.7% of these patients had OSA. SA patients were more likely to be younger, male, and had a high burden of comorbidities including heart failure, obstructive lung disease, diabetes, and kidney disease (Table 1).
SA, specifically OSA is prevalent among contemporary US patients admitted for AVR-and have a high burden of comorbidities. Meticulous screening for these patients may be warranted.
|Predictors of Sleep Apnea||Odds Ratio||P-value||[95% Confidence. Interval]|
|Chronic Obstructive Airway Disease||1.850843||<0.001||1.69||2.02|
|Chronic Kidney Disease||1.12||0.036||1.01||1.24|