Author + information
- Received April 12, 2017
- Accepted May 2, 2017
- Published online September 18, 2017.
- Juan Gabriel Córdoba-Soriano, MD∗ (, )
- Antonio Gutiérrez-Díez, MD,
- Arsenio Gallardo López, MD and
- Jesús Jiménez-Mazuecos, MD
- Interventional Cardiology Unit, Cardiology Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
- ↵∗Address for correspondence:
Dr. Juan Gabriel Córdoba-Soriano, Hermanos Falcó 37, 02008, Albacete, Spain.
The use of bioresorbable vascular scaffolds (BVS) in aortocoronary grafts has been scarcely reported in the literature, with some isolated cases (1–3) and a unicentric series of 6 cases (4). In pivotal trials, saphenous vein grafts (SVGs) were also excluded, and have been poorly represented in large registries. However, in recent times, great concern has been raised about the increase of target lesion failure with these devices, which seem to occur at the time of the most potential benefit expected, at long term.
A 68-year-old diabetic man with history of aortocoronary revascularization surgery in 1989 and 2001, first with an SVG to the left anterior descending artery (LAD) and an SVG to first obtuse marginal branch, and second with the left internal mammary artery to the LAD and an SVG to second obtuse marginal branch, with permeability of all grafts except SVG-first-obtuse-marginal-branch in 2006, presented in 2013 with unstable angina for a critical stenosis in the body of the SVG to second obtuse marginal branch (Figure 1A, Online Video 1). A 3.5 mm × 28 mm BVS (ABSORB, Abbott Vascular, Santa Clara, California) was implanted according to the so-called pre-dilatation, proper sizing and post-dilatation technique with an excellent angiographic result (Figure 1B, Online Video 2). An angiographic control performed 17 months later for atypical chest pain showed sustained success of the device with a late luminal loss of 0.14 mm (Figure 1C, Online Video 3). At 47 months, new catheterization was performed due to unstable angina that showed a severe focal restenosis (Figure 1D, Online Video 4). The optical frequency domain imaging (Figures 1a to 1i, Online Video 5) showed incomplete BVS resorption, signs of neointimal hyperplasia as high-intensity homogeneous tissue (Figures 1b, 1g, and 1h), signs of neoatherosclerosis with presence of lipid tissue with high posterior attenuation (Figure 1c), and layered restenosis with heterogeneous tissue and irregular luminal border at the point of greatest obstruction (Figures 1d to 1f). It is possible that a different resorption velocity of the BVS in SVG triggered this very late restenosis, the first reported in this location.
For supplemental videos and their legends, please see the online version of this article.
The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received April 12, 2017.
- Accepted May 2, 2017.
- 2017 American College of Cardiology Foundation
- Yew K.L.
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