JACC: Cardiovascular Interventions
Clinical Research - Editorial Comment
The 5 Ts of Bifurcation Intervention: Type, Technique, Two Stents, T-Stenting, Trials
Ron Waksman and Laurent Bonello
Table 1
Table 1
Comparison of Bifurcation Studies in the DES Era
| Ge et al. (14) | Yanagi et al. (18) | Moussa et al. (17) | Di Mario et al. (19) | Tsuchida et al. (20) | Pan et al. (12) | Sharma (16) | Steigen et al. (9) | Hoye et al. (15) | Gunnes et al. (10) | Routledge et al. (1) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| n | 181 | 141 | 120 | 150 | 324 | 205 | 200 | 413 | 281 | 424 | 477 |
| Stent type | SES/PES | SES | SES | PES | SES | SES/PES | SES | SES | SES/PES | SES | SES/PES |
| Number of stents/lesions | 2 | 1 + provisional | 2 | 1 vs. 2 | n/a | 1+ provisional | 2 | 1 vs. 2 | 2 | 2 | 1+ provisional |
| Technique | Crush | n/a | Crush | All | n/a | T-stenting | SKS | n/a | Crush | Culotte Crush | Provisional T-stenting |
| Final kissing balloon (%) | 64.1 | 53.4 | 87.5 | 74 | n/a | 46 | n/a | 53 | 50.6 | Crush 88.8 Culotte 93.9 | 95.4 |
| Duration of follow-up, months | 9 | 6 ± 2 | 6 | 12 | 12 | 24 | 9 ± 2 | 6 | 9 | 8 | 24 |
| TLR (%) | 14.9 | 2 | 11.3 | 15.3 | n/a | 8.3 | 4 | 1.5 | 9.7 | n/a | 5.2 |
| TVR (%) | 17.1 | 0 | 12.2 | 18.6 | n/a | n/a | n/a | 2 | 11 | n/a | 8.9 |
| Stent thrombosis (%) | 4.4 | 0 | 1.7 | 2.7 | 1.5 | 0.5 | 1 | 0.2 | 4.3 | n/a | 3.6 |
| Death | 1.1 | 0 | 0.9 | 2⁎ | 0.9 | 1.5 | 2 | 1.2 | 1.3 | n/a | 5.4 |
| MI | 11.6 | 0 | 0 | 0.7 | 5.9 | 2.4 | 4 | 0.2 | 9.2 | n/a | 1.8 |
| MACE | 26.5 | 2 | 3 | 21.3 | 13.3 | 17.6 | 9 | 3.1 | 16.5 | Crush 4.3 Culotte 3.7 | 13.7 |
DES = drug-eluting stent(s); MACE = major adverse cardiac events; MI = myocardial infarction; PES = paclitaxel-eluting stent(s); SES = sirolimus-eluting stent(s); SKS = simultaneous kissing stents; TLR = target lesion revascularization; TVR = target vessel revascularization.
↵⁎ Cardiac death.
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