Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 Mechanisms of Platelet Activation and Inhibition
Platelet activation and mechanism of action of antiplatelet agents. ADP = adenosine diphosphate; ATP = adenosine triphosphate; CD40L = CD 40 ligand; COX = cyclooxygenase; GP = glycoprotein; PAI = plasminogen activator inhibitor; PDGF = platelet-derived growth factor TXA2 = thromboxane A2; vWF = von Willebrand factor. Adapted from Mehta SR, Yusuf S. Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention. J Am Coll Cardiol 2003;41 Suppl S:79S–88S.
|
