In-Hospital and 1-Year Outcomes Among Unselected Percutaneous Coronary Intervention Patients Treated With Either Sirolimus- or Paclitaxel-Eluting StentsResults From the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) Registry
Victor Novack, MD, PhD*,
Donald Cutlip, MD*, ,
Neal Kleiman, MD ,
Michael Pencina, PhD*,
Laura Mauri, MD, MSc*, ,
Chen-Hsing Yen, MS*,
Peter Berger, MD||,
Steven Goldberg, MD¶,
Mirle Kellett, MD#,
Ronald Waksman, MD**,
Mun Hong, MD,
Albert E. Raizner, MD,
David J. Cohen, MD, MSc,*
* Harvard Clinical Research Institute, Boston, Massachusetts
Beth Israel Deaconess Medical Center, Boston, Massachusetts
The Methodist DeBakey Heart Center, Houston, Texas
Brigham Women's Hospital, Boston, Massachusetts
|| Geisinger Clinic, Danville, Pennsylvania
¶ University of Washington Medical Center, Seattle, Washington
# Maine Medical Center, Portland, Maine
** Washington Hospital Center, Washington, DC
St. Luke's-Roosevelt Hospital Center, New York, New York
Saint-Luke's Mid America Heart Institute, Kansas City, Missouri
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Figure 2 Kaplan-Meier Survival Curves
Kaplan-Meier survival curves for time to cardiac death or myocardial infarction (MI) (A), time to definite or probable stent thrombosis (B), and time to target lesion revascularization (C). PES = paclitaxel-eluting stent(s); SES = sirolimus-eluting stent(s).
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Figure 3 Cox Proportional Hazard Regression Derived Hazard Ratios
Cox proportional hazard regression derived hazard ratios comparing SES versus PES for the end points of cardiac death or MI (A), target lesion revascularization (B), and stent thrombosis (C) at 12 months (with 95% confidence interval). Hazard ratios are derived from risk-adjustment models with sequential inclusion of baseline clinical characteristics, lesion characteristics, procedural characteristics, and site characteristics as described in the Methods section. Abbreviations as in Figure 2.
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Figure 4 Adjusted Hazard Ratios (SES vs. PES) for Cardiac Death or MI and TLR
Adjusted hazard ratios (SES vs. PES) for cardiac death or MI (A) and TLR (B) among pre-specified subgroups. ACS = acute coronary syndrome; DM = diabetes mellitus; TLR = target lesion revascularization; other abbreviations as in Figure 2.
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