A Meta-Analysis of 3,773 Patients Treated With Percutaneous Coronary Intervention or Surgery for Unprotected Left Main Coronary Artery Stenosis
Hursh Naik, MD*,
Anthony J. White, MBBS, PhD*,
Tarun Chakravarty, MD*,
James Forrester, MD*,
Gregory Fontana, MD*,
Saibal Kar, MD*,
Prediman K. Shah, MD*,
Robert E. Weiss, PhD ,
Raj Makkar, MD*,*
* Cedars-Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California
Department of Biostatistics, University of California, Los Angeles School of Public Health, Los Angeles, California
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Figure 1 Search Process Algorithm
Flow chart demonstrating the resulting 10 studies that were analyzed. Subgroups of left main patients were not included due to the possibility of added confounding. ACC = American College of Cardiology; AHA = American Heart Association; CABG = coronary artery bypass grafting; PCI = percutaneous coronary intervention; TCT = Trans-Catheter Therapeutics.
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Figure 2 Odds Ratio of Mortality Following Treatment for ULMCA Disease in PCI Versus CABG Patients
Odds ratio of mortality (with confidence intervals) following treatment for unprotected left main coronary artery (ULMCA) disease after 1, 2, and 3 years. Year 1: 1,393 PCI patients and 1,932 CABG patients; year 2: 528 PCI patients and 890 CABG patients; and year 3: 263 PCI patients and 578 CABG patients. Abbreviations as in Figure 1.
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Figure 3 Odds Ratio of MACCE in PCI Versus CABG Patients
Odds ratio of major adverse cardiac and cerebrovascular events (MACCE) (death, myocardial infarction, and stroke) in PCI patients versus CABG patients after 1, 2, and 3 years. Year 1: 1,239 PCI patients and 1,614 CABG patients; year 2: 432 PCI patients and 652 CABG patients; and year 3: 236 PCI patients and 451 CABG patients. Abbreviations as in Figure 1.
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Figure 4 Odds Ratio of TVR in PCI Versus CABG Patients
Odds ratio of target vessel revascularization (TVR) in PCI patients versus CABG patients at 1, 2, and 3 years. Year 1: 1,240 PCI patients and 1,692 CABG patients; year 2: 417 PCI patients and 699 CABG patients; and year 3: 211 PCI patients and 447 CABG patients. Abbreviations as in Figure 1.
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