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J Am Coll Cardiol Intv, 2008; 1:369-378, doi:10.1016/j.jcin.2008.03.019
© 2008 by the American College of Cardiology Foundation
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Prevalence, Predictors, and Impact of Conservative Medical Management for Patients With Non–ST-Segment Elevation Acute Coronary Syndromes Who Have Angiographically Documented Significant Coronary Disease

Mark Y. Chan, MD, MHS*, Kenneth W. Mahaffey, MD, FACC*, Lena J. Sun, MS*, Karen S. Pieper, MS*, Harvey D. White, MD, FACC{dagger}, Philip E. Aylward, MD, FACC{ddagger}, James J. Ferguson, MD, FACC§, Robert M. Califf, MD, FACC*, Matthew T. Roe, MD, MHS, FACC*,*

* Duke Clinical Research Institute, Durham, North Carolina
{dagger} Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
{ddagger} Flinders Medical Center, Adelaide, Australia
§ Texas Heart Institute, St. Luke's-Episcopal Hospital, Houston, Texas.


Figure 1
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Figure 1 Subject Flow

CABG = coronary artery bypass grafting; CAD = coronary artery disease; MM = conservative medical management; PCI = percutaneous coronary intervention.

 

Figure 2
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Figure 2 Late or Repeat Revascularization

*Discharge landmark time point of discharge, or 7 days if hospitalization was prolonged; {dagger}Includes re-exploration. Abbreviations as in Figure 1.

 

Figure 3
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Figure 3 In-Hospital and Post-Discharge Mortality

(A) Death from catheterization through discharge. (B) Death from discharge* through 1 year. Log-rank p values: conservative medical management versus PCI, p < 0.0001; conservative medical management versus CABG, p = 0.08. *Landmark time point of discharge, or 7 days if hospitalization was prolonged. Abbreviations as in Figure 1.

 

Figure 4
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Figure 4 Overall Mortality From Randomization Through 1 Year

Log-rank MM versus PCI, <0.0001; MM versus CABG, 0.52. Abbreviations as in Figure 1.

 




 
   
 
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