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J Am Coll Cardiol Intv, 2008; 1:168-173, doi:10.1016/j.jcin.2007.12.007
© 2008 by the American College of Cardiology Foundation
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In Vivo Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Detecting Small Degrees of In-Stent Neointima After Stent Implantation

Yoriyasu Suzuki, MD*,1, Fumiaki Ikeno, MD*,1, Tomomi Koizumi, MD, PhD*, Fermin Tio, MD{dagger}, Alan C. Yeung, MD, FACC*, Paul G. Yock, MD, FACC*, Peter J. Fitzgerald, MD, PhD, FACC*, William F. Fearon, MD, FACC*,*

* Division of Cardiovascular Medicine, Stanford University, Stanford, California
{dagger} University of Texas Health Science Center, San Antonio, Texas.


Figure 1
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Figure 1 OCT System

(A) M2 optical coherence tomography (OCT) (LightLab Imaging Inc.) imaging system. (B) ImageWire imaging probe. (C) Motor drive unit. (D) Occlusion catheter.

 

Figure 2
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Figure 2 Methodology

The Schema shows how to analyze optical coherence tomography (OCT) and intravascular ultrasound (IVUS) on the basis of the histological correlation. ISN = in-stent neointima.

 

Figure 3
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Figure 3 Representative Images

(A, B) Histology. (C, D) Optical coherence tomography (OCT). (E, F) Intravascular ultrasound (IVUS). Insets in A, C, and E show the high magnification of in-stent neointima covering stent struts.

 

Figure 4
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Figure 4 The Correlation Between OCT and Histology

(A) Lumen area. (B) Stent area. (C) In-stent neointima area. OCT = optical coherence tomography.

 

Figure 5
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Figure 5 Receiver-Operating Characteristic Curve

Solid line = optical coherence tomography. Dotted line = intravascular ultrasound.

 




 
   
 
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