Percutaneous Coronary Intervention for Chronic Stable AnginaA Reassessment
David R. Holmes, Jr, MD, FACC*,*,
Bernard J. Gersh, MB, ChB, DPhil, FACC*,1,
Patrick Whitlow, MD, FACC ,2,
Spencer B. King, III, MD, MACC ,3,
James T. Dove, MD, FACC
* Department of Cardiology, Division of Cardiovascular Disease and Internal Medicine, Mayo Clinic, Rochester, Minnesota
The Cleveland Clinic, Cleveland, Ohio
Fuqua Heart Center, Atlanta, Georgia
Prairie Cardiovascular Consultants, Southern Illinois University School of Medicine, Springfield, Illinois.
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Figure 1 Results of a Meta-Analysis of Studies on the Effect of PCI Versus Medical Therapy on Cardiac Death or MI
CI = confidence interval; PCI = percutaneous coronary intervention; pt = patients. Data from Katritsis et al. (15).
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Figure 2 Meta-Analysis of Stents Versus Conventional PTCA on Rate of Death or MI, Angiographic Restenosis, and Repeat PTCA
MI = myocardial infarction; PTCA = percutaneous transluminal coronary angioplasty. Data from Brophy et al. (21).
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Figure 3 Evaluation of the Effects of Routine Stenting Versus Conventional PTCA on Death and Reinfarction
(A) Effects on death; (B) effects on reinfarction. AS = Angioplasty or Stent; BENESTENT = Belgian Netherlands Stent Study; BESMART = Bestent in Small Arteries; BOSS = Balloon Optimization versus Stent Study; CADILLAC = Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications; DESTINI = Doppler Endpoint Stenting International Investigation; EPISTENT = Evaluation of Platelet IIb/IIIa Inhibitor for Stenting; FRESCO = Florence Randomized Elective Stenting in Acute Coronary Occlusions; FROST = French Optimal Stenting Trial; GRAMI = Gianturco-Roubin in Acute Myocardial Infarction; ISAR-SMART = Intracoronary Stenting or Angioplasty for Restenosis Reduction in Small Arteries; MAJIC = Mayo-Japan Investigation for Chronic Total Occlusion; OCBAS = Optimal Coronary Balloon Angioplasty With Provisional Stenting Versus Primary Stent; OPUS = Optimum Percutaneous Transluminal Coronary Angioplasty Compared With Routine Stent Strategy; OR = odds ratio; PASTA= Primary Angioplasty Versus Stent Implantation in Acute Myocardial Infarction; SARECCO = Stent or Angioplasty after Recanalization of Chronic Coronary Occlusions; SISA = Stenting in Small Arteries; SPACTO = Stent versus Percutaneous Angioplasty in Chronic Total Occlusion; Stent-PAMI = Stent Primary Angioplasty in MI; STENTUIM = Immediate Coronary Angioplasty with Elective Wiktor Stent Implantation Compared with Conventional Balloon Angioplasty in Acute Myocardial Infarction; TOSCA = Total Occlusion Study of Canada; other abbreviations as in Figure 2. Reprinted from Brophy et al. (22).
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Figure 4 Analysis of Randomized Trials of Sirolimus Versus BMS on Death, MI, and TLR
BMS = bare-metal stent; MI = myocardial infarction; TLR = target lesion revascularization. Reprinted from Stone et al. (23).
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