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J Am Coll Cardiol Intv, 2010; 3:114-118, doi:10.1016/j.jcin.2009.09.017
© 2010 by the American College of Cardiology Foundation
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Clinical Research

Use of Balloon Aortic Valvuloplasty to Size the Aortic Annulus Before Implantation of a Balloon-Expandable Transcatheter Heart Valve

Vasilis C. Babaliaros, MD*, Zahid Junagadhwalla, MD, Stamatios Lerakis, MD, Vinod Thourani, MD, David Liff, MD, Edward Chen, MD, Thomas Vassiliades, MD, Clay Chappell, MD, Nathan Gross, BS, Ateet Patel, BA, Sharon Howell, BS, Jacob T. Green, MD, Emir Veledar, PhD, Robert Guyton, MD, Peter C. Block, MD

Andreas Gruentzig Cardiovascular Center, Emory University Hospital, Atlanta, Georgia

* Reprint requests and correspondence: Dr. Vasilis C. Babaliaros, Department of Cardiology, Emory University Hospital, 1364 Clifton Road, Suite F606, Atlanta, Georgia 30322 (Email: Vbabali{at}emory.edu).

Objectives: Our aim was to describe the use of balloon aortic valvuloplasty (BAV) to select proper transcatheter heart valve (THV) size.

Background: Transesophageal echocardiogram (TEE) measurement alone of the aortic annulus may not be adequate to select a THV size. BAV can more accurately size the aortic annulus. We report our experience using this strategy in patients undergoing THV implantation.

Methods: Twenty-seven patients underwent sizing of the aortic annulus by BAV and TEE. We implanted the minimal THV size that was greater than the annulus measured by BAV.

Results: The annulus measured by TEE was 21.3 ± 1.6 mm and by BAV was 22.6 ± 1.8 mm (p < 0.001). The number of balloon inflations was 2.7 ± 0.7 (range 2 to 4), and the balloon sizes used were 22.0 ± 1.8 mm (range 20 to 25 mm). Fourteen patients (52%) required upsizing of the initial balloon suggested by TEE; rapid pacing duration was 8 ± 1.3 s (range 6 to 11 s). No change in aortic insufficiency or hemodynamic instability occurred with BAV. Fifteen patients (56%) received a 23-mm THV; 12 patients a 26-mm THV. No coronary occlusion, annular damage, or THV embolization occurred. Paravalvular leak was grade ≤1 in all patients. In 7 patients (26%), balloon sizing resulted in selection of a specific THV size that could not be done by TEE alone.

Conclusions: BAV sizing of the aortic annulus is safe and is an important adjunct to TEE when selecting THV size. Implanting the minimal THV greater than the BAV annulus size resulted in no adverse events. These data suggest that use of BAV for THV selection may improve the safety and efficacy of THV implantation.

Key Words: percutaneous • transcatheter • aortic • valve • annulus • aortic stenosis • balloon aortic valvuloplasty

Abbreviations and Acronyms
  AIBP = additional intraballoon pressure
  BAV = balloon aortic valvuloplasty
  PVL = paravalvular leak
  TEE = transesophageal echocardiogram
  THV = transcatheter heart valve






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